The coalition's Social Science Working Group and co-signatories have published a viewpoint on vaccine equity, arguing that a temporary TRIPS waiver is needed for COVID-19 vaccines and other medicines. Vaccine inequity is amongst the most significant social justice issues of our generation, and it poses a major threat to the global COVID-19 response. Urgent action is needed to improve equity and bring an end to the COVID-19 pandemic, including in low- and middle-income countries.